PhD student Endocrine Tumor Laboratory

Job description

The Endocrine Tumor Laboratory at Erasmus MC has a strong legacy of translational research dedicated to advancing the diagnosis and treatment of endocrine disorders, with a primary focus on pituitary, adrenal, and neuroendocrine tumors. It is one of the few centers worldwide with extensive expertise in culturing endocrine tumor tissues. In recent years, the lab has adopted multi-omics technologies to enable a more in-depth analysis of endocrine tumors, utilizing a combination of omics approaches alongside advanced 3D cell culture models. These efforts aim to:

• Uncover pathophysiological mechanisms of endocrine tumors
• Identify molecular drivers of tumor growth and hormone production in endocrine tumors
• Discover novel diagnostic, predictive, and therapeutic biomarkers
• Evaluate drug sensitivity and identify new therapeutic targets

You will join a project focused on uncovering the molecular mechanisms that drive the initiation and progression of endocrine tumors. The project integrates cutting-edge CRISPR-based gene editing and advanced cell culture models with both bulk and single-cell multi-omics approaches. In addition to advancing our understanding of the molecular pathways underlying these tumors, you will contribute to translational research, where discoveries are developed toward potential clinical applications. You will be part of a dynamic, multidisciplinary, and international research environment, working closely with both basic scientists and clinical researchers.

Work environment

The Erasmus MC stands for a healthy population and excellence in healthcare. Through groundbreaking research, education, and patient care, we strive to push boundaries and set new standards. With a strong commitment to improving today’s healthcare and shaping the public health of tomorrow, we bring together high-level expertise in a state-of-the-art environment. Our researchers and clinicians have access to the latest technologies and advanced facilities, enabling innovation and impact at the highest level.

Qualifications and skills

We are looking for a highly motivated PhD student with an MSc in Molecular Biology, Biomedical Sciences, Biotechnology, or a related field. You have proven research experience in mammalian cell culture, as well as in molecular and cellular biology techniques such as DNA cloning, PCR, qPCR, Western blotting, and immunofluorescence. Bioinformatics skills, or a strong motivation to acquire them, are important for this position.


Additional requirements and preferences:

• Experience with omics technologies is a plus.
• Experience with CRISPR/Cas9 is a plus.
• Proficiency in written and spoken English.
• Excellent communication skills and the ability to work both independently and as part of a team.
• Strong motivation for research, a problem-solving mindset, and the ability to work autonomously and within a team.
• Organizational skills.

Before you apply please check our conditions for employment.

Terms of employment

• You will receive a temporary position for 4 years. 
• The gross monthly salary amounts a minimum of € 3.108,- and a maximum of € 3.939,-.
• Excellent fringe benefits, such as a 13th month that is already paid out in November and an individual travel expense package.
• Pension insurance with ABP. We take care of approximately 2/3 of the monthly contribution.
• Special benefits, such as an in-company physiotherapist and bicycle repairer. And there is also a gym where you can work on your fitness after work.

More information

For more information about this position, please contact Dr. ir. Eskeatnaf Mulugeta via mail e.mulugeta@erasmusmc.nl or telephone number at 06 464 878 35.

No agencies please.