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Postdoctoral fellow on the hematopoietic stem cell niche in leukemia

  • Research & Education
  • 36 hours
  • Hematology

  • Closing date 30-03-2020
  • 03.10.20.TDdH

Job description

The Department of Hematology at the Erasmus Medical Center Cancer Institute runs an ambitious and internationally recognized research program in the field of stem cell biology, bone marrow failure and leukemogenesis. The overall goal of our laboratory is to gain a better understanding of the cellular elements and molecular pathways driving leukemogenesis. Specifically, we aim to understand the interplay between the bone marrow microenvironment and hematopoietic cells in physiology and disease.

The postdoctoral projects will focus on dissecting the role of signaling in the stem cell niche in development, regeneration and in malignant transformation in the hematopoietic system. We will exploit mouse modeling and state-of-the art molecular tools and strive to translate insights to human disease, exploring therapeutic modalities aimed at targeting niche signaling to drive regeneration and treat bone marrow disease.

Work environment

The Department of Hematology hosts a highly interactive group of researchers and physicians with a common goal to conduct basic and translational research in the field of molecular aspects of bone marrow malignancies and to improve patient health. It accommodates a state of the art infrastructure for cell biological, genomic and clinically applied research.

Qualifications and skills

The position should appeal to most scientists who want to perform cutting edge basic/translational research applying in vitro and in vivo modeling with the ultimate goal to develop novel therapeutics. Furthermore the following skills and qualifications are required:

  • Demonstrated track record in basic/translational research (at least one publication with impact),
  • Expertise in hematology or stem cell biology,
  • Profound hands-on experience in molecular biological assays and techniques (FACS, RNA/DNASeq, Crispr-Cas9),
  • Solid hands-on experience in (hematological) mouse models (including bone marrow transplantation), 
  • Excellent oral and written communication skills in English,
  • Highly motivated and a team-player.

Before you apply please check our conditions for employment.

Terms of employment

The gross monthly salary amounts a minimum of € 2.826,- (scale 10) and a maximum of € 5.226,- (scale 11), depending on your level of education and relevant experience and based on a full-time working week of 36 hours. The terms of employment are in accordance with the Collective Bargaining Agreement for University Medical Centers (CAO UMC).

Information and application

For more information about this position, please contact Principal Investigator Marc Raaijmakers, phone number: +31 (0)10 704 47 23 or e-mail: For queries regarding your application, please contact Jerry Chandansingh, Recruiter, by phone number: +31 (0)6 500 310 06.
If you are excited by the thought of this position and would like to apply, please do so by using the application form on our website.

No agencies please.

Erasmus MC

Pioneering, pushing boundaries and leading: in healthcare, education and research

Our roots lie in Rotterdam, a city and port of international standing. We are the most innovative university medical center in the Netherlands and one of the world’s leading centers of scientific research. With passion and dedication we are committed to achieve a healthy population and pursuing excellence in healthcare through research and teaching. We have access to the latest equipment and techniques. A working environment that gets the best out of people.

Learn more about our ambitions