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PhD student on the Project 'DohART-NET', a Marie Sklodowska-Curie Innovative Training Networks

PeRicOnceptional Programming of HEalTh Training Network
  • Research & Education
  • 36 hours
  • Obstetrics and Gynecology

  • Closing date 10-03-2020
  • 05.03.20.TS

Job description

MSCA ITN founded project "DohART-NET” focusing on key aspects of altered conditions during the periconceptional (PC) period of gamete maturation. The DohART-NET project focusses on the integration of pre-clinical (animal and stem cell-models) and clinical studies and apply data linkage, bioinformatics and network science for the identification and validation of mechanisms of diseases common in early development. The project will exploit a new understanding to promote efficient disease prevention and potential personalised therapeutic interventions in both the general and ART populations to overcome adverse disease pathways. DohART-NET is optimized for training Early Stage Researchers (ESRs) due to the facts that: i) the topic is progressive and much needed to improve public health over several generations, and it is integrating basic pre-clinical, translational clinical and in silico modeling approaches, iii) the partnership has a highly multi- and interdisciplinary scientific and training expertise and excellence, iv) there is an existing synergy by collaborations and links that the partners wish to strengthen both in science and lasting training programs in a highly inter-sectorial setting. ESRs will strongly benefit from a network of internationally recognized scientists in the field of basic and clinical science (translational research), involving departments like Genetics, Bioinformatics, Obstetrics and Gynaecology, and the participation of companies with relevant interests and expertise in the field.

The applicant will develop a multidisciplinary project focused on investigating the impact of preconceptional maternal obesity and underlying pathways of embryonic, fetal and newborn health. The study will be conducted in the unique and ongoing Rotterdam Periconceptional Cohort (Predict study). The Predict study is designed as a tertiary hospital-based, prospective open birth cohort study. Embryonic, fetal and newborn health will be investigated longitudinally using state-of-the-art imaging techniques like three-dimensional ultrasound and virtual reality techniques. Using these techniques different structures, e.g. in the brain, can be investigated in detail and very reliable in relation to maternal obesity. Besides ultrasound imaging data, also questionnaires and blood samples are available for study.

Work environment

DohART-NET Network: BioTalentum Ltd. (Hungary), University of Cambridge (UK), University of Manchester (UK), University of Southampton (UK), Erasmus University Medical Center (Netherlands), CeMM (Austria), Ludwig Maximilian University of Munich (Germany), MWM GmbH (Germany), Universitair Ziekenhuis Brussel (Belgium), IVI Valencia (Spain).

Qualifications and skills

The ideal candidate should have solid knowledge in Clinical Medicine (and Obstetrics and Gynaecology), ideally with a Masters level in Medicine and/or Epidemiology. Research experience is a big advantage and practical experience in handling large databases and in biostatistics and or bioinformatics would be preferred, but not required. The project implies a series of secondments at partner labs for additional training. The successful candidate will participate in the network’s training activities and work placements at the laboratories of the participating academic and industrial teams. Regular meetings and workshops within the EU-funded DohART-NET International Training Network will supplement the training and support provided at Szent Istvan University.

Applicants should also meet the following eligibility criteria:

  •  a background in Clinical Medicine or Epidemiology (Master’s degree),
  • not already have a PhD,
  • less than 4 years research experience at the signature of the contract (measured from the time the Master’s degree has been obtained),
  • not have spent more than 12 months in the country (Hungary) of the host/recruiting institution in the 3 years prior to selection,
  • excellent knowledge of the spoken and written English language,
  • excellent communication and team working skills.

Before you apply please check our conditions for employment.

Terms of employment

You will receive a temporary position for 3 years. The gross monthly salary is € 2.422 ,- in the 1st year and increases to €3.103,- in the 4th year (scale OIO). The terms of employment are according to the Collective Bargaining Agreement for Dutch University Medical Centers (CAO UMC).

Information and application

For more information about this position, please contact Prof. dr. R.P.M. Steegers-Theunissen, Professor in Periconception Epidemiology, e-mail: r.steegers@erasmusmc.nl or Dr. Melek Rousian, Postdoc Periconception Epidemiology, e-mail: m.rousian@erasmusmc.nl. For queries regarding your application, please contact Jerry Chandansingh, Recruiter, by phone number: +31 (0)6 500 310 06.

If you are excited by the thought of this position and would like to apply, please do so by using the application form on our website and include CV, a motivation letter including research career goals, skills and experience  and 2 letters of recommendation. 

No agencies please.

Erasmus MC

Pioneering, pushing boundaries and leading: in healthcare, education and research

Our roots lie in Rotterdam, a city and port of international standing. We are the most innovative university medical center in the Netherlands and one of the world’s leading centers of scientific research. With passion and dedication we are committed to achieve a healthy population and pursuing excellence in healthcare through research and teaching. We have access to the latest equipment and techniques. A working environment that gets the best out of people.

Learn more about our ambitions