Atherosclerosis is an inflammatory and lipid-driven disease of the artery walls. In the carotid arteries, it may trigger a stroke, and as such is a major cause of death and long-term disability. Current treatment consists of surgical intervention, based on the occurrence of symptoms (e.g., transient ischemic attack) and the degree of arterial narrowing. The tissue composition of atherosclerotic plaque has important consequences for the risk of a specific plaque to cause a stroke, but is currently not taken available for deciding on a treatment course.
In this project we will use photoacoustic imaging (PAI), a relatively new imaging modality, to visualize carotid artery plaque composition in ex vivo samples and in patients. An integrated echo/PAI system will be assembled and characterized, and then deployed in a clinical study after approval by the appropriate boards. We will study the relation between plaque composition and clinical presentation, and investigate factors such as medication status and diabetes.
The Department of Biomedical Engineering (Thorax Center) is a group of over 50 researchers performing highly innovative research in cardiovascular diagnosis and therapy. We focus on translational research in ultrasound imaging and image processing, ultrasound contrast agents for molecular imaging and drug delivery, intravascular imaging techniques and hemodynamics. The Biomedical Engineering Department is composed of engineers, biologists and clinicians, closely collaborating on cutting-edge cardiovascular research. Its vibrant working environment attracts highly motivated researchers from all over the world. This project is embedded in the Invasive Imaging research group which is part of the BME department.
Qualifications and skills
We are looking for an enthusiastic PhD student that meets the following requirements:
- a recent Master’s degree in (Technical) Medicine, Clinical Technology or similar. Your responsibilities will include enrolling patients in the clinical study, so a Dutch BIG registration is an advantage.
- keen interest in new technologies and a curiosity and drive to demonstrate their value in clinical practice;
- experience in measurements/experimental setups. Programming skills (Matlab, Python, C++) are a plus;
- creative, pro-active with good analytical skills and a sound academic attitude;
- excellent communication skills in English, both in writing and speaking;
- a good teamplayer and able to work in a collaborative environment with other PhD students/researchers and supporting institutions.
Before you apply please check our conditions for employment.
Terms of employment
You will receive a temporary position for 4 years. The gross monthly salary is € 2.495,- in the 1st year and increases to € 3.196,- in the 4th year (scale OIO). The terms of employment are according to the Collective Bargaining Agreement for Dutch University Medical Centers (CAO UMC).
Information and application
For more information about this position, please contact Dr. Gijs van Soest, phone number: +31 (0)10 704 46 38 or Sharon Sewell, secretary, phone number: +31 (0)10 704 40 30. For queries regarding your application, please contact Jerry Chandansingh, Recruiter, by phone number: +31 (0)6 500 310 06.
If you are excited by the thought of this position and would like to apply, please do so by using the application form on our website.
No agencies please.