Postdoc on human disease models

Job description

We have an opening for a postdoctoral researcher in the field of vascular disease with a specific focus on aorta aneurysms. The research aims at creating in vitro disease models to gain new insights into the development of the disease. Your goal will be to design novel methods classification of genetic variants by determining the effect(s) of genetic variants on cell behavior and the vascular wall using the newly designed disease models.

Work environment

You will be part of multidisciplinary team consisting of clinical geneticists, bioinformaticians and a pathobiologist. You will be supported by a part-time technician, and we expect you be able to support and partially supervise a PhD student. You will have access to a large clinical and genetic database linked to a biobank. This is a 3.5-year position and we expect you to submit grant applications successfully during this time to firmly establish this research for the future.

Qualifications and skills

• Tissue culture, organs-on-chips and molecular biology techniques including the ability to generate expression-constructs and cell transfections of primary human cell lines.
• Advanced microscopy techniques.
• RNA and protein expression analysis by Northern and Western and qPCR.
• In addition, bioinformatics expertise regarding pathway analysis and affinity for DNA sequencing analysis would be desirable.

Before you apply please check our conditions for employment.

Terms of employment

The gross monthly salary amounts a maximum of € 4.615,- (scale 10), depending on your level of education and relevant experience and based on a full-time working week of 36 hours. The terms of employment are in accordance with the Collective Bargaining Agreement for University Medical Centers (CAO UMC).

Information and application

For more information about this position, please contact:

• Heleen van Beusekom, pathobiologist, e-mail: h.vanbeusekom@erasmusmc.nl,
• Arne IJpma, bioinformatician e-maila.ijpma@erasmusmc.nl, or
• Danielle Majoor-Krakauer, clinical geneticist, e-mail: d.majoor-krakauer@erasmusmc.nl.

For queries regarding your application, please contact Jerry Chandansingh, Recruiter, by phone number: +31 (0)6 500 310 06.  If you are excited by the thought of this position and would like to apply, please do so by using the application form on our website.

No agencies please.