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PhD candidate Biomarker Research in Kidney Transplantation

  • Closing date 30-06-2022
  • 22.34.22.TD
  • 36 hours
  • Research university
  • Research & Education

Questions? Contact our recruiter

  • Closing date 30-06-2022
  • 22.34.22.TD

Job description

You will join our research line focusing on the value of non- (or minimally) invasive biomarkers in the diagnosis and prediction of acute rejection after kidney transplantation. Markers of interest include (in addition to clinical characteristics) donor-derived cell-free DNA, protein profiles (proteomics) and urinary chemokines. Acute rejection of a kidney transplant occurs in up to 20% of patients and is associated with poor transplantation outcome. A kidney biopsy is the gold standard to diagnose rejection, though a biopsy is an invasive procedure and puts patients at risk for procedure-related complications. Therefore one of the priorities in the transplantation field is the identification of non- (or minimally) invasive biomarkers capable to supplement (or even replace) the histopathological score.

You will combine available datasets to search for an optimal combination of parameters in the identification and prediction of rejection. An additional question is whether these biomarkers could guide anti-rejection treatment as well as monitor response to anti-rejection treatment. Timely and optimal treatment is necessary to prevent further graft damage and improve both patient and graft survival.

Work environment

The Erasmus MC is one of the largest kidney transplantation centers in Europe, where annually ~150-200 kidney transplantations are performed. The section Nephrology and Transplantation of the Dept. of Internal Medicine is involved in kidney transplant patient care, research and education, and is part of the recently established Erasmus MC Transplant Institute. We offer a dynamic team of 20 employees including postdocs, PhD students and research technicians. Our research focusses on biomarkers, immunological aspects of kidney transplantation and kidney organoids, all with the aim to improve graft survival and patient well-being after kidney transplantation.

Qualifications and skills

You are an enthusiastic life scientist with good bioinformatic and biostatical skills. Knowledge of computational methods and ‘big data’ analysis (genomics/proteomics) is preferable. Suitable candidates will have a master degree in biology, biomedical sciences, life sciences, or a related discipline. You are highly motivated, dedicated, independent and capable of working in a multidisciplinary environment.

Before you apply please check our conditions for employment.

Terms of employment

  • You will receive a temporary position for 3 years.
  • The gross monthly salary is € 2.570 ,- in the 1st year and increases to € 3.125,- in the 3th year (scale OIO).
  • Excellent fringe benefits, such as a 13th month that is already paid out in November and a individual travel expense package.
  • Pension insurance with ABP. We take care of approximately 2/3 of the monthly contribution.
  • Special benefits, such as a incompany physiotherapist and bicycle repairer. And there is also a gym where you can work on your fitness after work.

The terms of employment are in accordance with the Collective Bargaining Agreement for University Medical Centers (CAO UMC).

More information

For more information about this position, please contact Karin Boer, PhD, Assistant Professor : +31 (0)10 703 54 19. For queries regarding your application, please contact Jeanette dos Santos Gomes, Recruiter +31 (0)6 500 310 07.

If you are excited by the thought of this position and would like to apply, please do so by using the application form on our website.

No agencies please.

Application proces

Step 1 - Apply

Did we get you excited about this position? Submit your application through the application button. You will receive a confirmation of receipt from our recruiter right away.

Step 2 - Selection

Based on your application, we check to see if there is a fit between us. We will let you know as soon as possible whether you are invited for an interview.

Step 3 - Interview

You have been invited for an interview, great! In this first meeting we get to know each other and see if You can form an idea of the position, the department and Erasmus MC. If the interview goes well usually a second interview follows.

Step 4 - Offer and terms

It’s a match! Your future manager will discuss your salary and employment with you. You will also receive more information about our other terms of employment.

Step 5 - Getting started

Your first working day has come! We are more than happy to have you. Your new department will give you a warm welcome and provide you with all the information you need. Enjoy your job at Erasmus MC!

Contact me

Jeanette dos Santos Gomes

Jeanette dos Santos Gomes
Erasmus MC

Pioneering, pushing boundaries and leading: in healthcare, education and research

Erasmus MC is an international leading academic hospital in Rotterdam. We are recognized as a world-class scientific research organization aiming to improve our understanding of diseases and disorders and helps to predict, treat and prevent them. We have access to the latest equipment and techniques. A working environment that gets the best out of people.

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Apply for PhD candidate Biomarker Research in Kidney Transplantation