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Postdoctoral researcher in Urology and pathology

You will be part of the Erasmus MC Urothelial Cancer Research Group (EUCRG) and will be working on patient data and biomaterials collected from the national prospective IMPASSE study.
  • Closing date 03-07-2022
  • 22.37.22.TDdH
  • 36 hours
  • PhD
  • Research & Education
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Questions? Contact our recruiter

  • Closing date 03-07-2022
  • 22.37.22.TDdH

Job description

You will be part of the Erasmus MC Urothelial Cancer Research Group (EUCRG) and will be working on patient data and biomaterials collected from the national prospective IMPASSE study. The IMPASSE study aims to improve bladder cancer patient stratification in collaboration with the diagnostic company InnoSIGN by using their OncoSignal platform. Secondly, the project aims to investigate previously identified novel druggable gene candidates by performing ex vivo drug screens on patient-derived organoids (PDOs) and an in-depth analysis of response to treatment. The final objective of the project is to setup a proof-of-concept clinical trial in which PDO-guided treatment recommendation is offered to urological patients. Multiple techniques will be used for execution of the project, such as ex vivo culturing of PDOs, image mass cytometry, next-generation sequencing, incuCyte analyses, light sheet microscopy.

You will supervise a research technician and will work in close collaboration with a PhD student on a parallel project. And will manage the project, plan, execute and troubleshoot experiments in a timely manner. There will be regular meetings with the principal investigators of the project and update on project progress. The postdoc is expected to write progress reports and other documents needed for the project. You will keep up-to-date with the literature, write manuscripts, present the data at departmental meetings and scientific conferences and write follow-up grant applications for project continuation.
 

Work environment

The Departments of Urology and Pathology have excellent logistics to support the project and state-of-the-art facilities and equipment for the translational research of the IMPASSE project. Research is conducted within expert teams that have experience in PDO culture, molecular biology, next-generation sequencing, mass cytometry and light sheet microscopy. Erasmus University Medical Center, is one of the largest academic medical centers in Europe providing an outstanding environment for research, education and patient care. Erasmus University Medical Center is located in Rotterdam, The Netherlands, an exciting and thriving urban environment. Position is open from September/October 2022 and is for 3 years.

Qualifications and skills

  • You should hold a PhD in biomedical sciences, molecular biology, biochemistry, medical/bio technology, and have first author publications/preprints in leading peer-reviewed journals within the respective field and a trackrecord for presentations at scientific conferences.
  • You should have a strong interest in the area of PDO culture, drug screening, translational research and project management.
  • You must have excellent oral and written communication skills in English. Preferably also good Dutch as communication with participating hospitals is mostly in Dutch.
  • You should be flexible as biomaterials from patients come in at all times, be motivated to work hard and able to work independently and in teams.  

Experience in PDO culturing, preclinical tumor models, an immunology background, translation research background and drug screening is highly desirable.
You are expected to collaborate closely with clinicians at the department of Urology and Pathology within the Erasmus MC. Communication skills should be excellent and a proactive attitude a must as the project (multiple national hospitals) will be managed by you.

Before you apply please check our conditions for employment.

Terms of employment

  • We offer a full-time contract of 36 hours per week in an inspiring and challenging work environment with excellent fringe benefits.
  • You will receive a temporary position for 3 years.
  • The gross monthly salary amounts a maximum of € 4.707,- (scale 10), depending on your level of education and relevant experience and based on a full-time working week of 36 hours.
  • The terms of employment are in accordance with the Collective Bargaining Agreement for University Medical Centers (CAO UMC).

More information

For more information about this position, please contact Tahlita Zuiverloon, MD PhD, department of Urology,  t.zuiverloon@erasmusmc.nl or Prof. Tokameh Mahmoudi, department of Urology and Pathology, t.mahmoudi@erasmusmc.nl. For queries regarding your application, please contact Diana Brusik-van Houten via d.brusik-vanhouten@erasmusmc.nl or +3110 704 36 75

No agencies please.

Application proces

Step 1 - Apply

Did we get you excited about this position? Submit your application through the application button. You will receive a confirmation of receipt from our recruiter right away.

Step 2 - Selection

Based on your application, we check to see if there is a fit between us. We will let you know as soon as possible whether you are invited for an interview.

Step 3 - Interview

You have been invited for an interview, great! In this first meeting we get to know each other and see if You can form an idea of the position, the department and Erasmus MC. If the interview goes well usually a second interview follows.

Step 4 - Offer and terms

It’s a match! Your future manager will discuss your salary and employment with you. You will also receive more information about our other terms of employment.

Step 5 - Getting started

Your first working day has come! We are more than happy to have you. Your new department will give you a warm welcome and provide you with all the information you need. Enjoy your job at Erasmus MC!

Contact me

Donja Grootscholten
Recruiter

Donja Grootscholten
Erasmus MC

Pioneering, pushing boundaries and leading: in healthcare, education and research

Erasmus MC is an international leading academic hospital in Rotterdam. We are recognized as a world-class scientific research organization aiming to improve our understanding of diseases and disorders and helps to predict, treat and prevent them. We have access to the latest equipment and techniques. A working environment that gets the best out of people.

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