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PhD on investigating the impact of preconceptional maternal obesity and underlying pathways of embryonic, fetal and newborn health

DohART-NET: a Marie Sklodowska-Curie Innovative Training Networks,PeRicOnceptional Programming of HEalTh Training Network. 
  • Wetenschap en Onderzoek
  • 36 uur
  • Obstetrics and Gynecology

  • Sluit op 06-08-2019
  • 26.05.19.TS

Functie inhoud

MSCA ITN founded project "DohART-NET” focusing on key aspects of altered conditions during the periconceptional (PC) period of gamete maturation. The DohART-NET project focus on the integration of pre-clinical (animal and stem cell-models) and clinical studies and apply data linkage, bioinformatics and network science for the identification and validation of mechanisms of diseases common in early development. The Project will exploit a new understanding to promote efficient disease prevention and potential personalised therapeutic interventions in both the general and ART populations to overcome adverse disease pathways. DohART-NET is optimized for training Early Stage Researchers (ESRs) due to the facts that: i) the topic is progressive and much needed to improve public health over several generations, and it is integrating basic pre-clinical, translational clinical and in silico modeling approaches, iii) the partnership has a highly multi- and interdisciplinary scientific and training expertise and excellence, iv) there is an existing synergy by collaborations and links that the partners wish to strengthen both in science and lasting training programs in a highly inter-sectorial setting. ESRs will strongly benefit from a network of internationally recognized scientists in the field of basic and clinical science (translational research), involving departments like Genetics, Bioinformatics, Obstetrics and Gynaecology, and the participation of companies with relevant interests and expertise in the field.

DohART-NET Network: BioTalentum Ltd. (Hungary), University of Cambridge (UK), University of Manchester (UK), University of Southampton (UK), Erasmus University Medical Center (Netherlands), CeMM (Austria), Ludwig Maximilian University of Munich (Germany), MWM GmbH (Germany), Universitair Ziekenhuis Brussel (Belgium), IVI Valencia (Spain). 

The applicant will develop a multidisciplinary project focused on investigating the impact of preconceptional maternal obesity and underlying pathways of embryonic, fetal and newborn health. The study will be conducted in the unique and ongoing Rotterdam Periconceptional Cohort (Predict study). The Predict study is designed as a tertiary hospital-based, prospective open birth cohort study. Embryonic, fetal and newborn health will be investigated longitudinally using state-of-the-art imaging techniques like three-dimensional ultrasound and virtual reality techniques. Using these techniques different structures, e.g. in the brain, can be investigated in detail and very reliable in relation to maternal obesity. Besides ultrasound imaging data, also questionnaires and blood samples are available for study.

The ideal candidate should have solid knowledge in Clinical Medicine (and Obstetrics and Gynaecology), ideally with a Masters level in Medicine and/or Epidemiology. Research experience is a big advantage and practical experience in handling large databases and in biostatistics and or bioinformatics would be preferred, but not required. The project implies a series of secondments at partner labs for additional training. The successful candidate will participate in the network’s training activities and work placements at the laboratories of the participating academic and industrial teams. Regular meetings and workshops within the EU-funded DohART-NET International Training Network will supplement the training and support provided at Szent Istvan University.
 

Werkomgeving

A healthy population and excellence in healthcare through research and education. This is what Erasmus MC stands for. Conducting groundbreaking work, pushing boundaries and leading the way. In research, education, and healthcare. We are practical people with a high level of expertise, working hard to improve and renew the healthcare of today and the public health of tomorrow.

Profiel

Applicants should meet the following eligibility criteria:
• Background in Clinical Medicine or Epidemiology (Master’s degree);
• No PhD title; 
• Less than 4 years research experience at the signature of the contract (measured from the time
  the Master’s degree has been obtained); 
• Have not spent more than 12 months in the country (Hungary) of the host/recruiting institution in the
  3 years prior to selection; 
• Excellent knowledge of the spoken and written English language; 
• Excellent communication and team working skills.

Being able to present a certificate of good conduct, a valid proof of identity, diploma's and/ or relevant registration such as BIG/ RGS are conditions for the appointment

Wat bieden wij

You will receive a temporary position for 3 years. The gross monthly salary is € 2.750,- in the 1st year and increases to € 3.020,- in the 3rd year (scale OIO). The terms of employment are according to the Collective Bargaining Agreement for Dutch University Medical Centers (CAO UMC).

Inlichtingen en solliciteren

For more information about this position, please contact Prof. dr. R.P.M. Steegers-Theunissen, Professor in periconception Epidemiology, e-mail: r.steegers@erasmusmc.nl or Dr. Melek Rousian, post-doc Periconception epidemiology, e-mail: m.rousian@erasmusmc.nl. For queries regarding your application, please contact Jerry Chandansingh, Recruiter, by phone number: +31 (0)6 500 310 06.

If you are excited by the thought of this position and would like to apply, please do so by using the application form on our website.

Acquisitie naar aanleiding van deze advertentie is niet gewenst.

Afbeelding

Werken aan beter worden is altijd nieuwsgierig zijn

Erasmus MC is het grootste medisch onderzoekscentrum van Nederland. We zijn internationaal toonaangevend op het gebied van wetenschappelijk onderzoek en onderwijs. Wij vergroten de kennis over ziektes van vandaag en verbeteren de gezondheid van morgen. We verbinden de nieuwste wetenschappelijke inzichten zodat onze patiënten hier optimaal van profiteren.

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